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Marc Pfeffer presented the results of PARADISE-MI at ACC last week. As discussed previously on CVCTCardiobrief, sacubitril/valsartan did not reduce the primary outcome compared to…
Long Unsuccessful Heart Failure Drug Once Again At Center Of Controversy
–The long, strange 30-year journey of BiDil. It’s been buried in the avalanche of related news but there’s an interesting and somewhat bizarre cardiology angle…
A New Novartis Heart Failure Drug Might Be A Blockbuster
I try to avoid using words like “blockbuster” and “breakthrough” when writing about new drugs and treatments. I’ve been disappointed too many times. But, though…
Possible Cognitive Benefits Found In Dementia Patients Taking Centrally Acting ACE Inhibitors
An observational study from Ireland raises the intriguing possibility that certain blood pressure lowering drugs, centrally acting ACE inhibitors, may help slow the cognitive decline that is…
Many CHF Patients Not Receiving– Or Getting Benefits From– High Dose ACE Inhibitors And ARBs
Although current guidelines recommend that ACE inhibitors and angiotensin-receptor blockers (ARBs) be used in high doses in patients with congestive heart failure, many CHF patients…