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SGLT2 inhibitors are probably the hottest new drug on the scene in cardiology this year. They were bandied about for lowering glucose in diabetes but…
What Happened to Hospital Attendance: A Perception Trap
Hospital admissions for almost everything came to almost a complete halt this year because of the pandemic. In March and April 2020, people stopped coming…
James Stein Interview with SAMSON senior author Darrel Francis: Statin Side Effects – The Symptoms are Real
The SAMSON trial recruited patients who had given up statins for good due to side effects. Why was the trial needed and what do the…
Cardiology Research: Business As Usual During the Pandemic
The middle of a raging pandemic is no time for business-as-usual research studies, especially when the studies falsely purport to shed light on that pandemic. Such papers have all the appearance of high quality science. They have a ton of data and a lot of big words but they’re incapable of providing reliable or useful information that can aid in our understanding and control of the health emergency.
COVID-19 Heart: We have all the gear but no idea
We have plenty of sophisticated gear to understand heart problems. For COVID-19, we’ve seen Troponin blood tests, cardiac MRIs and echo. For example, cardiac injury was associated with a higher risk of death in hospitalized patients. And yet, we have no answers to the questions that matter for clinical practice.
Darrel Francis Interview with Matthew Budoff: Demistifying the EVAPORATE trial of icosapent ethyl
Darrel Francis speaks to Matthew Budoff about EVAPORATE trial and asks about the plaque progression in the placebo arm and the choice of placebo. EVAPORATE was a follow-on mechanistic study from REDUCE-IT and was presented at the European Society of Cardiology 2020 and published in the European Heart Journal.
Missed MI in the emergency department and early stress testing
People with chest pain go to the Emergency Department (ED). They get checked out. Some get diagnosed with acute coronary syndrome. Some get diagnosed with other conditions. And some get told there is nothing wrong.
CVCT Forum 2020 Preview: Tackling the Research Crisis During the COVID-19 Pandemic
The current COVID-19 pandemic has exerted an unprecedented impact across the globe. More than 29.4 million cases have been reported worldwide, including over 930,000 deaths.…
In the Eye of the COVID-19 Storm
Editor’s note: James Stein has been writing a series of posts on Facebook on the COVID-19 crisis, providing a sensible overview of current events for nonprofessionals…